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UFOP researchers publish scientific paper in partnership with Poles

UFOP researchers Katiane Nogueira, from the Department of Biological Sciences (Departamento de Ciências Biológicas - DECBI), and Leonardo Brandão Nogueira from the Department of Geology (Departamento de Geologia - Degeo), have published a scientific paper on bladder cancer in the Journal of Pharmaceutical Analysis, in collaboration with Polish researchers Thomasz Ruman and Joanna Niziol from the Rzeszów University of Technology.

The article "Metabolomic and elemental profiling of blood serum in bladder cancer" is the result of the study carried out by researchers in the attempt to outline metabolic and elementary profiles and ascertain potential biomarkers of bladder cancer.

Bladder tissue samples were examined using three methods: Nuclear Magnetic Resonance (NMR), Laser Desorption/Ionization Mass Spectrometry (LDI-MS) and Inductively Coupled Plasma-Optical Emission Spectroscopy ( (ICP-OES). All analyses were performed at UFOP laboratories.

The results indicate the presence of a profile of biometals in the evaluated organs that can be validated for bladder cancer screening using only blood tests.

The researcher Katiane Nogueira, who coordinates the Laboratory of Neurobiology and Biomaterials, emphasizes that the partnership with Poles "greatly improved the internationalization of the University", and that the research "has an enormous impact, for science in general as well as for the area of biotechnology". The collaboration also opened up the possibility of future use of the same biomarker for the identification of Alzheimer's disease.

The research began in 2018, with the UFOP researchers going to the Polytechnic University of Rzeszów, Poland, when it was noticed the possibility of mutual collaboration between the institutions.
The visit was carried out through a public notice from the Erasmus+ international mobility program, promoted by the International Relations Office (Diretoria de Relações Internacionais - DRI).

Check out the paper.